St. James the Greater (meaning the Elder) and his brother John were partners in the fishing business with two other brothers, Peter and Andrew. They all lived in Bethsaida, a village on the north shore of the Sea of Galilee. His mother was a sister of the Blessed Virgin Mary, and he would have known Jesus from childhood. He is one of those that Jesus called Boanerges, "sons of thunder," the brother of St. John the Evangelist and the son of Zebedee the fisherman from Galilee.
Along with Peter and John, James was part of the inner circle of Jesus, the ones who witnessed the Transfiguration, and who were witnesses to certain of His miracles, such as the raising of the daughter of Jairus. Like his brother, James was active in the work of evangelization after the death of Jesus, and there is some evidence that he went to Spain after our Lord's resurrection. In fact, the great Cathedral of Santiago de Compostela witnesses to that probability.
St. James' prominence and his presence in Jerusalem was well known. Scarcely a dozen years after the Resurrection he was arrested and executed by King Herod Agrippa. This was followed by the arrest of Peter also, so his death must have been part of a purge of Christian leaders by Agrippa, who saw the new Christian movement as a threat.
Jesus had foretold this kind of fate when He prophesied that James and his brother John would "drink of the same chalice" of suffering as Himself. Along with their mother's request, the two brothers had asked to be seated at the right of Jesus and at His left in His kingdom, and Jesus told them that they would be with Him, but it turned out to be in a far different way than they expected.
Grant, O merciful God, that as thine holy Apostle Saint James, leaving his father and all that he had, without delay was obedient unto the calling of thy Son Jesus Christ, and followed him: so we, forsaking all worldly and carnal affections, may be evermore ready to follow thy holy commandments; through Jesus Christ thy Son our Lord, who liveth and reigneth with thee, in the unity of the Holy Spirit, ever one God, world without end. Amen.