St. Anthony was born in Portugal and entered the Augustinian monastery of Sao Vicente in Lisbon when he was fifteen. When news of the Franciscan martyrs in Morocco reached him, he joined the Franciscans at Coimbra. At his own request, he was sent as a missionary to Morocco, but he became ill, and on his return journey his boat was driven off course and he landed in Sicily. He took part in St. Francis' famous Chapter of Mats in 1221 and was assigned to the Franciscan province of Romagna.
He became a preacher by accident. When a scheduled preacher did not show up for an ordination ceremony at Forli, the Franciscan superior told Anthony to go into the pulpit. His eloquence stirred everyone, and he was assigned to preach throughout northern Italy. Because of his success in converting heretics, he was called the "Hammer of Heretics" and because of his learning, St. Francis himself appointed him a teacher of theology.
St. Anthony of Padua was such a forceful preacher that shops closed when he came to town, and people stayed all night in church to be present for his sermons. He became associated with Padua because he made this city his residence and the center of his great preaching mission.
After a series of Lenten sermons in 1231, Anthony's strength gave out and he went into seclusion at Camposanpiero but soon had to be carried back to Padua. He did not reach the city but was taken to the Poor Clare convent at Arcella, where he died. He was thirty-six years old, and the whole city of Padua turned out in mourning for his passing.
Grant, O Lord, that the solemn festival of thy holy Confessor Saint Anthony may bring gladness to thy Church: that being defended by thy succour in all things spiritual, we may be found worthy to attain to everlasting felicity; through Jesus Christ thy Son our Lord, who liveth and reigneth with thee, in the unity of the Holy Spirit, ever one God, world without end. Amen.